CafeMinor

**Can Prediction Markets Become a Rational Shield Against Social Media's "Mad Rhetoric"?**
Ethereum co-founder Vitalik Buterin recently shared an interesting observation on Farcaster: in an era flooded with exaggerated claims and panic-mongering on social media, prediction markets are playing an increasingly important role as "truth calibrators."
**The Imbalance of Incentives on Social Media**
On platforms like X, the cost of creating sensational content is extremely low. Take the example of the UK civil war—some KOLs post claims that "a UK civil war is inevitable" to attract attention, but th

**Ethereum Spot ETF Market Shows Significant Outflow Signals**
Market data from SoSoValue reveals a notable shift in Ethereum spot ETF dynamics on January 9 (Eastern Time). The broader Ethereum ETF ecosystem experienced substantial capital movements, with total net redemptions hitting $93.8151 million during the 24-hour period—signaling potential investor caution or profit-taking activity.
**BlackRock's ETHA Leads Outflow Activity**
Among all Ethereum spot ETF products, BlackRock's ETHA captured the largest redemption volume yesterday, registering a single-day net outflow of $83.7783 million.

## Losmapimod Shows Tangible Clinical Benefits in FSHD Treatment: Fulcrum Therapeutics' Phase 2b Trial Data Published
Fulcrum Therapeutics has released Phase 2b clinical trial results for losmapimod in treating facioscapulohumeral muscular dystrophy (FSHD), with findings now published in *The Lancet Neurology*. The data reveal promising improvements across multiple clinical measures, advancing understanding of how this investigational therapy may address this rare progressive muscle disorder.
**Trial Design and Patient Demographics**
The ReDUX4 trial enrolled 80 participants with FSHD type 1 a