Resilient Portfolios: Which Companies Have the Greatest Profitability Potential in 2025

The Shift in Markets and the Search for Opportunities

While 2024 closed with historic milestones in returns, 2025 has painted a radically different picture. The implementation of new tariffs by the US administration —10% base on all imports, 50% toward the European Union, 55% accumulated on China, and 24% on Japan— initially triggered a panic reaction in global stock markets. US, European, and Asian indices simultaneously turned negative.

However, after the volatility of March-April, markets have experienced a notable rebound. Far from the initial panic, major indices are recovering to all-time highs, creating both risks and opportunities for attentive investors. In this context, identifying best companies to invest in requires a balance between financial strength, growth potential, and adaptability amid trade uncertainty.

Comparative Analysis: The 15 Companies with the Highest Growth Potential

The following selection groups together leading global companies prioritizing short/medium-term profitability potential, moderate risk, and sectoral and geographic diversification. These assets are available on standard investment platforms and offer exposure to major economies:

Data as of July 7, 2025

Why These Companies Deserve Attention in the Current Environment

The above selection responds to specific criteria of resilience and potential within a scenario of persistent trade tensions.

Defensive sectors with structural demand: In energy, both Exxon Mobil and BHP Group benefit from sustained commodity prices and global infrastructure renewal. BHP, specialized in iron, copper, and nickel, leverages demand from emerging economies and energy transitions.

Financial intermediaries in privileged positions: JPMorgan Chase, as the largest US bank, is positioned to capitalize on high interest rates while maintaining diversification in commercial banking, investment, and card services. Its financial strength allows it to seize international opportunities even in uncertain cycles.

Innovation in health with secular tailwinds: Novo Nordisk leads in diabetes and obesity with next-generation products. Despite recent competitive pressures, its 43% margins and robust R&D spending support long-term growth expectations.

Luxury and consumer recovery post-correction: LVMH presents opportunities derived from excessive corrections. Expansion in Japan (double-digit growth in 2024), Middle East (+6% regional), and India creates future demand hotspots that counter current pressures.

Accelerated technological transition: TSMC, a key manufacturer of advanced semiconductors, benefits from global demand for AI chips. ASML, the sole provider of extreme ultraviolet lithography (EUV) machines, controls a strategic bottleneck in frontier semiconductor manufacturing.

Tech giants: stability with growth: Microsoft, Apple, Amazon, and Alphabet combine financial strength with exposure to secular trends (cloud, AI, digital commerce). Although valuation corrections are present, their operating margins and investment capacities sustain growth trajectories.

Accelerated Chinese recovery: Alibaba, after years of regulatory pressure, repositions with a three-year plan of $52 billion in AI and cloud infrastructure. The 22% growth in net profit in Q1 2025 (driven by Cloud Intelligence +18%) suggests a reversal of previous trends.

Five Strategic Selections: Where to Concentrate Capital

Within the previous expanded portfolio, these five assets concentrate the most attractive profitability catalysts for 2025, combining solid operational execution, market leadership, and adjusted valuations:

1. Novo Nordisk: Correction as an entry point

Novo Nordisk fell 27% in March 2025 —its worst month since 2002— due to concerns about increasing competition (especially from Eli Lilly with Zepbound) and disappointment in phase III data of the drug CagriSema. However, the company’s fundamentals remain intact.

In 2024, sales grew 26% to 290.4 billion Danish kroner (≈$42.1 billion). The company completed the acquisition of Catalent for $16.5 billion in December 2024, expanding production capacity. In March 2025, it secured rights to LX9851 (Lexicon Pharmaceuticals) for $1 billion, adding a new mechanism against obesity.

The dual GLP-1/amylin molecule amycretin achieved 24% weight loss in early studies. Margins of 43% and a robust pipeline support long-term expectations even amid current competitive pressures. Global demand for therapies for diabetes and obesity remains structurally upward.

2. LVMH: Opportunity in regional recovery

LVMH suffered declines of 6.7% in January and 7.7% on April 15 after modest Q1 2025 results (revenue of €20.3 billion, -3%). US tariffs (20% in April, reduced to 10% until July 9 with a threat of 50%) pressured valuations given significant US revenues.

Nevertheless, the stock correction creates opportunity. In 2024, LVMH reported revenues of €84.7 billion with recurring operating profit of €19.6 billion (marginal operating margin 23.1%), demonstrating resilience even in a challenging economic environment.

LVMH’s diversification —including Louis Vuitton, Dior, Givenchy, Fendi, Celine, Tiffany & Co., Bulgari, and Sephora— spans fashion, perfumes, cosmetics, jewelry, and wines. Growth hotspots emerge in Japan (double-digit sales in 2024), Middle East (+6%), and India, with new Louis Vuitton and Dior stores in Mumbai. Innovation through the AI platform Dreamscape for personalization of prices and experiences enhances competitiveness.

3. ASML: Exposure to semiconductors without substitutes

ASML lost about 30% of its value over the past year due to reduced spending by key clients (Intel, Samsung) on advanced equipment. However, TSMC and SK Hynix maintain high capex due to AI demand, supporting continued demand for ASML’s EUV lithography systems.

In 2024, ASML achieved net sales of €28.3 billion and net income of €7.6 billion (margins of 51.3%). Q4 sales reached €9.3 billion, exceeding expectations. Q1 2025 reported €7.7 billion in sales with a record gross margin of 54%, confirming an annual guidance of €30-35 billion.

Dutch trade restrictions (January 15, 2025) will cut sales to China by 10-15%, but without altering the annual outlook. Demand for advanced AI chips and high-performance computing systems sustains the persistent need for EUV systems. The recent correction could present an opportunity for semiconductor exposure.

( 4. Microsoft: AI ecosystem with record margins

Microsoft experienced a ~20% correction from all-time highs in Q1 2025, reaching an intraday low of $367.24 on March 31. Valuation doubts and a relative slowdown in Azure weighed, along with FTC investigations into monopolistic practices in cloud and cybersecurity.

However, in April 2025, it reported solid Q3 fiscal results: revenue of $70.1 billion with a 46% operating margin. Azure and cloud services grew 33%, reflecting accelerated adoption of AI capabilities.

In fiscal year 2024, Microsoft reported revenue of $245.1 billion )+16% annually###, operating income of $109.4 billion (+24%), and net income of $88.1 billion (+22%). Between May and July 2025, it announced over 15,000 layoffs to redirect resources to AI, streamlining its structure. Solid financial position and aggressive investment in AI and cloud underpin long-term potential.

( 5. Alibaba: Repositioning with domestic catalysts

Alibaba fell 35% from its 2024 highs in January 2025, reflecting concerns over massive investments in AI/cloud and trade tensions. Subsequent volatility included a +40% rebound in mid-February and a -7% decline after March results considered weak.

Fundamentally, Q4 2024 reported revenue of ¥280.2 billion )+8% annually###. Q1 2025 showed revenue of ¥236.45 billion with adjusted net profit growing 22%, driven by Cloud Intelligence (+18%).

The three-year plan of $52 billion in AI/cloud infrastructure and a campaign of ¥50 billion in coupons to revitalize domestic consumption generate tangible catalysts. Capitalizing on current low prices could result in significant future profitability.